Vancomycin Use Associated with Coagulase-negative Staphylococcus spp. Blood Cultures in Children
by April Thompkins, PharmD, Michelle Mitchell, MD, Sue Kehl, PhD, Evelyn Kuhn, PhD, Tracy Zembles, PharmD, BCPS-AQID
"Blood cultures serve as the primary way to diagnose bacteremia in children. However, isolation of pathogenic organisms is impacted by several factors, including blood culture volume, number of cultures, collection technique, and timing in relation to starting antibiotics. Unfortunately, blood culture contamination is common in children, with a reported incidence of 0.5% to 22.8%. Bacteria most commonly identified as blood culture contaminants include: coagulase-negative Staphylococcus species (CoNS), Corynebacterium species, Bacillus species (other than anthracis), Micrococcus species, and Cutibacterium species. Among these, CoNS is the most common, accounting for 70-80% of all contaminated blood cultures."
Keywords: Adult, Child, Humans, Vancomycin, Blood Culture, Antimicrobial Stewardship, Micrococcus, Anti-Bacterial Agents, Coagulase, Length of Stay, Bacillus, Incidence, Bacteremia, Staphylococcus, Corynebacterium
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2020 September/October Table of Contents
"Blood cultures serve as the primary way to diagnose bacteremia in children. However, isolation of pathogenic organisms is impacted by several factors, including blood culture volume, number of cultures, collection technique, and timing in relation to starting antibiotics. Unfortunately, blood culture contamination is common in children, with a reported incidence of 0.5% to 22.8%. Bacteria most commonly identified as blood culture contaminants include: coagulase-negative Staphylococcus species (CoNS), Corynebacterium species, Bacillus species (other than anthracis), Micrococcus species, and Cutibacterium species. Among these, CoNS is the most common, accounting for 70-80% of all contaminated blood cultures."
Keywords: Adult, Child, Humans, Vancomycin, Blood Culture, Antimicrobial Stewardship, Micrococcus, Anti-Bacterial Agents, Coagulase, Length of Stay, Bacillus, Incidence, Bacteremia, Staphylococcus, Corynebacterium
Download PDF
2020 September/October Table of Contents